منابع مشابه
XMAP215: A Tip Tracker that Really Moves
XMAP215 is a microtubule plus-end binding protein implicated in modulating microtubule dynamics. In this issue, Brouhard et al. (2008) propose a new mechanism to explain how XMAP215 promotes microtubule growth. They report that XMAP215 moves with the growing microtubule plus ends where it catalyzes the addition of tubulin subunits.
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Fast growth of microtubules is essential for rapid assembly of the microtubule cytoskeleton during cell proliferation and differentiation. XMAP215 belongs to a conserved family of proteins that promote microtubule growth. To determine how XMAP215 accelerates growth, we developed a single-molecule assay to visualize directly XMAP215-GFP interacting with dynamic microtubules. XMAP215 binds free t...
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This article is a commentary on remarks made in a recent book [12] that perpetuate several myths about Brouwer and intuitionism. The footnote on page 279 of [12] is an unfortunate, historically and factually inaccurate, blemish on an otherwise remarkable book. In that footnote, in which Ok discusses Brouwer (who, incidentally, was normally known not as Jan but as Bertus, a shortening of his...
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ژورنال
عنوان ژورنال: Cell
سال: 2008
ISSN: 0092-8674
DOI: 10.1016/j.cell.2007.12.019